Showing posts with label counterfeit. Show all posts
Showing posts with label counterfeit. Show all posts

Wednesday, January 20, 2010

If You Don't Need to Poo, Your Weight Loss Drug Might Be Fake

Caveat emptor: The Consumerist reports that counterfeit versions of Alli -- an over-the-counter weight loss drug -- are being sold online.



Alli, a reduced-strength version of orlistat, a prescription drug used to treat obesity, works by "decreasing absorption of fat by the intestines, which reduces the number of calories you absorb." Orlistat, however, has a number of serious poo-related side effects, including:
  • Urgent need to defecate
  • Gas with an oily anal discharge (known colloqually as "sharting")
  • Loose stools or diarrhea
  • More frequent bowel movements
  • Hard-to-control bowel movements
Meanwhile, the fake version of Alli contains another weight loss drug altogether: sibutramine, which helps to boost satiety. In other words, it's supposed to make you feel full. Unfortunately, sibutramine is a controlled substance that's been linked to cardiovascular problems, including high blood pressure. Additionally:

The FDA also warns that "sibutramine is a drug that should not be used in certain patient populations or without physician oversight. Sibutramine can also interact in a harmful way with other medications the consumer may be taking."
Explosive diarrhea is (marginally) more appealing than suffering a heart attack, but not surprisingly, the best choice may be to ditch Alli altogether. According to the Mayo Clinic:

Alli can help you lose weight, but the weight loss likely won't be great — perhaps just a few pounds more than you would lose with diet and exercise alone. Only a small number of studies have evaluated the effectiveness of Alli. And many of the weight-loss estimates are based on studies conducted on its prescription-strength counterpart, Xenical.

The average weight loss for prescription-strength Xenical is modest — about 6 pounds greater than diet and exercise alone after one year. So at half the strength, Alli could conceivably result in an average of 3 pounds lost in a year in addition to the approximately 8 pounds you could expect to lose from diet and exercise alone.
No contest: I'll gladly take three pounds over a full year of uncontrollable shitting.